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KMID : 0378019720150090053
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New Medical Journal
1972 Volume.15 No. 9 p.53 ~ p.58
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Effects of Hypothalamic Lesions on the Regulations of Erythropoietic Response and Body Temperature in Rabbits
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Abstract
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To investigate the effects of hypothalamic lesion on the erythropoietic function and the regulation of body temperature, bilateral preoptic regions of rabbit hypothalamus were destroyed electrolytically.
The reticulocytes count, hematocrit and rectal temperature were evaluated to these lesioned animals and exposed to 8% oxygen environment for erythopoietic response to hypoxia.
The results obtained were as follows:
1. The reticulocytes and hematocrit values were decreased in the lesioned animals of preoptic region of hypothalamus.
2. Destruction of preoptic region of hypothalamus leads to decrease of rectal temperature.
3. There were no changes of erythropoietic responses to hypoxia in the preoptic lesioned ainmals. 4. Destruction of preoptic region of hypothalamus can not inhibit the erythropoietic response to hypoxia.
It was suggested that the regulating center for erythropoiesis and body temperature did not exist in a local point but in scattered area of hypothalamus.
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